guanine nucleotide

AIM: To study the effects of down-regulation of guanine nucleotide exchange protein 100 (GEP100) on the invasive ability of pancreatic cancer cell AsPC-1 in vitro.

目的：研究鸟嘌呤核苷酸交换蛋白100 (GEP100)基因沉默对胰腺癌细胞体外侵袭能力的影响。

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Guanine nucleotide Exchange Factor;

鸟苷酸交换因子；

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AIM: To study the alteration of the content of guanine nucleotide binding protein α subunits ( G α protein) in myocardium during shock, and the effect of naloxone ( NAL) on the G protein.

目的：研究失血致低血容量性休克大鼠心脏组织鸟苷酸结合蛋白（Guanine nucleotide-binding protein，G蛋白）含量的变化及纳络酮对其影响。

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Small GTPase proteins play a pivotal role as important molecular switches, containing four guanine nucleotide ( GTP/ GDP) binding ( GNB) domains and an effectors domain.

小GTPase蛋白作为重要的分子开关其结构域主要包括4个鸟苷酸（GTP/GDP）结合域及1个效应区。

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Small GTPases are monomeric guanine nucleotide binding proteins coupled to the α-subunit of heterotrimeric G proteins. All small GTPases belong to Ras superfamily.

小G蛋白是和异三聚体G蛋白α亚基偶联的单体鸟苷酸结合蛋白，所有的小G蛋白从属于Ras超家族。

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The subunit α_0 of guanine nucleotide-binding protein, in the areas of rat brain and spinal cord was localized by immunohistochemical methods.

本研究应用兔抗鸟核苷酸调节蛋白α0亚单位（简称α0）多克隆血清（抗体），采用免疫组织化学方法对大鼠脑和脊髓内一些结构中的α0作了定位观察。

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